- Graduate Student
- Hons. BSc - Neuroscience and Mental Health, Carleton University (2022)
- Contact: zacharysilver@cmail.carleton.ca OR zacharysilver6@gmail.com
Research Interest/Focus
My research focuses on the prenatal programming of metabolic function in an animal model of gestational
diabetes. We are specifically looking at how maternal hyperglycemia leads to alterations in the
placental and fetal hypothalamic transcriptomes, as well as anatomical and functional changes in these
regions, and how these changes may mediate the development of metabolic disorders in adulthood. This is
relevant because in humans, people born of gestational diabetes pregnancies are at increased risk of
developing metabolic disorders in adulthood, such as obesity, heart disease, and especially type 2
diabetes.
Publications
Deng, J., Zhou, F., Heybati, K., Zuo, Q. K., Ali, S., Hou, W., Wong, C. Y., Ba Ramaraju, H., Chang, O., Dhivagaran, T., & Silver, Z. (2022). Efficacy and safety of corticosteroid regimens for the treatment of hospitalized COVID-19 patients: a meta-analysis. Future Virology, 17(7), 463-489.
Deng, J., Zhou, F., Hou, W., Heybati, K., Ali, S., Chang, O., Silver, Z., Dhivagaran, T., Ba Ramaraju, H., Wong, C. Y., Kang Zuo, Q., Lapshina, E., & Mellet, M. (2022). Efficacy of lopinavir–ritonavir combination therapy for the treatment of hospitalized COVID-19 patients: a meta-analysis. Future Virology, 17(3).
Silver, Z., Abbott-Tate, S., Hyland, L., Sherratt, F., Woodside, B., & Abizaid, A. (2021). Ghrelin receptor signaling is not required for glucocorticoid-induced obesity in female mice. Journal of Endocrinology, 250(2), 37-48.
Deng, J., Zhou, F., Hou, W., Silver, Z., Yi Wong, C., Chang, O., Drakos, A., Kang Zuo, Q., & Huang, E. (2021). The prevalence of depressive symptoms, anxiety symptoms and sleep disturbance in higher education students during the COVID-19 pandemic: A systematic review and meta-analysis. Psychiatry Research, 301, eArticle 113863. https://doi.org/10.1016/j.psychres.2021.113863
Deng, J., Zhou, F., Heybati, K., Ali, S., Zuo, Q. K., Hou, W., Dhivagaran, T., Ba Ramaraju, H., Chang, O., Wong, C. Y., & Silver, Z. (2021). Efficacy of chloroquine and hydroxychloroquine for the treatment of hospitalized COVID-19 patients: a meta-analysis. Future Virology, 17(2).
Deng, J., Silver, Z., Huang, E., Zheng, E., Kavanagh, K., Wen, A., Cheng, W., Dobransky, J., Sanger, S., & Grammatopoulos, G. (2020). Pharmacological prevention of fractures in patients undergoing glucocorticoid therapies: a systematic review and network meta-analysis. Rheumatology, 60(2), 649-657.
Deng, J., Zhou, F., Hou, W., Silver, Z., Yi Wong, C., Chang, O., Huang, E., & Kang Zuo, Q. (2020). The prevalence of depression, anxiety, and sleep disturbances in COVID-19 patients: a meta-analysis. Annals of the New York Academy of Sciences, 1486(1), 90-111. https://doi.org/10.1111/nyas.14506
Deng, J., Silver, Z., Huang, E., Zheng, E., Kavanagh, K., & Panicker, J. (2020). The effect of calcium and vitamin D compounds on bone mineral density in patients undergoing glucocorticoid therapies: a network meta-analysis. Clinical Rheumatology, 40(2), 725-734. https://doi.org/10.1007/s10067-020-05294-y
Outside of the Lab
When I am not in the lab I like to run, lift weights, read comic books, watch sports, and spend time
with friends.